机构：[1]Shenzhen Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China[2]Post-Doctoral Research Center, Longgang Central Hospital of Shenzhen, Shenzhen, China[3]Department of Radiology, Zhouxin Medical Imaging and Health Screening Center, Xiamen, China[4]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China医技科室放射科首都医科大学宣武医院[5]Keck school of Medicine, University of Southern California, Los Angeles, California, USA
Background While reference values of left atrial (LA) deformation parameters in Western populations have been established, reference data in healthy Asian populations are limited. Purpose To establish age- and sex-specific reference values for LA strain and strain rate (SR) based on a large sample of healthy Chinese adults using magnetic resonance-feature tracking (MR-FT). Study Type Retrospective. Population Four hundred and eight healthy Chinese adults (220 males, aged 43.5 +/- 11.5 years; 188 females, aged 45.3 +/- 12.8 years). Field Strength/Sequence 1.5 T/balanced steady-state free precession. Assessment Reservoir strain (epsilon(s)), conduit strain (epsilon(e)), booster strain (epsilon(a)), peak positive SR (SRs), peak early negative SR (SRe), and peak late negative SR (SRa) were obtained by MR-FT. Statistical Tests We used Shapiro-Wilk test, Student's t-test, Mann-Whitney U-test, linear regression, and coefficient of determination (r(2)). Results Women demonstrated significantly greater LA strain (epsilon(s) [%]: 44.0 +/- 9.9 vs. 38.3 +/- 8.7; epsilon(e) [%]: 26.7 +/- 8.0 vs. 22.3 +/- 6.8; epsilon(a) [%]: 17.3 +/- 4.4 vs. 16.0 +/- 3.8) and SR (SRs [/second]: 1.8 +/- 0.5 vs. 1.6 +/- 0.4; SRe [/second]: -2.5 +/- 0.9 vs. -2.1 +/- 0.7; SRa [/second]: -1.9 +/- 0.6 vs. -1.8 +/- 0.5) than men. For both sexes, aging was significantly associated with decreased epsilon(s), SRs, epsilon(e), and SRe (r(2) = 0.07, r(2) = 0.05, r(2) = 0.19, and r(2) = 0.24 for men; r(2) = 0.13, r(2) = 0.11, r(2) = 0.31, and r(2) = 0.46 for women), and significantly increased epsilon(a) (r(2) = 0.03 and r(2) = 0.05 for men and women). There was no significant correlation between age and SRa in both sexes (P = 0.057 and P = 0.377 for men and women, respectively). Data Conclusion We provide age- and sex-specific reference values for LA strain and SR based on a large sample of healthy Chinese adults using MR-FT. Level of Evidence 3 Technical Efficacy Stage 5
第一作者机构：[1]Shenzhen Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China
共同第一作者：
通讯作者：
通讯机构：[1]Shenzhen Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China[3]Department of Radiology, Zhouxin Medical Imaging and Health Screening Center, Xiamen, China[4]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China[*1]Department of Radiology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China.
推荐引用方式(GB/T 7714)：
Yiyuan Gao,Zhen Zhang,Gengxiao Li,et al.Reference Values for Left Atrial Strain and Strain Rate Based on a Large Sample of Healthy Chinese Adults: An MR-Feature Tracking Study[J].JOURNAL OF MAGNETIC RESONANCE IMAGING.2021,54(6):1784-1793.doi:10.1002/jmri.27768.
APA：
Yiyuan Gao,Zhen Zhang,Gengxiao Li,Shanshan Zhou,Mingwu Lou...&Gerald M. Pohost.(2021).Reference Values for Left Atrial Strain and Strain Rate Based on a Large Sample of Healthy Chinese Adults: An MR-Feature Tracking Study.JOURNAL OF MAGNETIC RESONANCE IMAGING,54,(6)
MLA：
Yiyuan Gao,et al."Reference Values for Left Atrial Strain and Strain Rate Based on a Large Sample of Healthy Chinese Adults: An MR-Feature Tracking Study".JOURNAL OF MAGNETIC RESONANCE IMAGING 54..6(2021):1784-1793
