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Transcranial Focused Ultrasound Neuromodulation: A Review of the Excitatory and Inhibitory Effects on Brain Activity in Human and Animals.

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机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China, [2]Beijing Key Laboratory of Neuromodulation, Beijing, China, [3]Center of Epilepsy, Institute of Sleep and Consciousness Disorders, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China
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关键词: transcranial focused ultrasound neuromodulation non-invasive brain stimulation human animal

摘要:
Non-invasive neuromodulation technology is important for the treatment of brain diseases. The effects of focused ultrasound on neuronal activity have been investigated since the 1920s. Low intensity transcranial focused ultrasound (tFUS) can exert non-destructive mechanical pressure effects on cellular membranes and ion channels and has been shown to modulate the activity of peripheral nerves, spinal reflexes, the cortex, and even deep brain nuclei, such as the thalamus. It has obvious advantages in terms of security and spatial selectivity. This technology is considered to have broad application prospects in the treatment of neurodegenerative disorders and neuropsychiatric disorders. This review synthesizes animal and human research outcomes and offers an integrated description of the excitatory and inhibitory effects of tFUS in varying experimental and disease conditions.Copyright © 2021 Zhang, Pan, Wang, Liu and Hu.

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出版当年[2020]版:
大类 | 3 区 医学
小类 | 3 区 心理学 4 区 神经科学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 神经科学 3 区 心理学
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出版当年[2019]版:
Q2 PSYCHOLOGY Q3 NEUROSCIENCES
最新[2023]版:
Q2 PSYCHOLOGY Q3 NEUROSCIENCES

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第一作者机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China, [2]Beijing Key Laboratory of Neuromodulation, Beijing, China,
通讯作者:
通讯机构: [1]Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China, [2]Beijing Key Laboratory of Neuromodulation, Beijing, China,
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