当前位置: 首页 > 详情页

First-day intracranial pressure correlates with ICU mortality in subarachnoid hemorrhage patients: an analysis of the MIMIC-IV database

文献详情

资源类型:
WOS体系:
Pubmed体系:

收录情况: ◇ SCIE

机构: [1]Capital Med Univ, Xuanwu Hosp, Dept Neurosurg, Beijing, Peoples R China
出处:
ISSN:

关键词: subarachnoid hemorrhage intracranial pressure intensive care unit mortality time-series clustering MIMIC-IV database

摘要:
Background The purpose of this study was to explore the optimal intracranial pressure (ICP) distribution of subarachnoid hemorrhage (SAH) patients on the first day in the intensive care unit (ICU) using data mining methods.Methods Continuous ICP monitoring records of 176 SAH patients on the first ICU Day were collected from the MIMIC-IV database, comprising individuals treated at Beth Israel Deaconess Medical Center (Boston, MA) ICU between 2008 and 2019. Data underwent five-step processing: rounding (to hour point), missing value imputation, resampling, min-max normalization, and time-series clustering. Four unique clusters of the SAH cohort were identified, differing by daily average and variance of ICP. Propensity score estimation was used to determine the average treatment effect of ICP management on ICU mortality based on the X-tile recommended cut-off point.Results The study cohort comprised 176 patients (mean age 58.8 +/- 14.54 years; 58.0% [102/176] female) who met the inclusion criteria. The daily average was the only statistically significant factor in the propensity score estimation. A daily average ICP of 14 mmHg was identified as the cut-off point. The group with a daily average ICP above or below the cut-off point was an independent ICU mortality predictor in the multivariate analysis, with the largest odds ratio value among included variables. Notably, the daily average ICP was higher in ICU deaths than in survived patients under similar first-day fluid balance (ICU deaths vs. survived patients: PPearson = 0.002, R2 = 0.25; PPearson = 0.016, R2 = 0.04).Conclusion In the study cohort collected from MIMIC-IV SAH patients, using 14 mmHg as the cut-off point for the daily average ICP on the first ICU Day demonstrated favorable ICU mortality outcomes.

基金:
语种:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2025]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 神经科学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 神经科学
JCR分区:
出版当年[2023]版:
Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES
最新[2024]版:
Q2 CLINICAL NEUROLOGY Q3 NEUROSCIENCES

影响因子: 最新[2024版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版] 出版后一年[2024版]

第一作者:
第一作者机构: [1]Capital Med Univ, Xuanwu Hosp, Dept Neurosurg, Beijing, Peoples R China
共同第一作者:
通讯作者:
推荐引用方式(GB/T 7714):
APA:
MLA:

相关文献

[1]Comparison of different intensive care scoring systems and Glasgow Aneurysm score for aortic aneurysm in predicting 28-day mortality: a retrospective cohort study from MIMIC-IV database [2]Intracranial pressure responsiveness to positive end-expiratory pressure is influenced by chest wall elastance: a physiological study in patients with aneurysmal subarachnoid hemorrhage [3]Can EuroSCORE II Predict the Mortality and Length of Intensive Care Unit Stay after Total Aortic Arch Replacement with Stented Elephant Trunk Implantation for DeBakey Type I Aortic Dissection? [4]The impact of initiation timing of continuous renal replacement therapy on outcomes in critically ill patients with acute kidney injury a retrospective study from the MIMIC-IV database [5]Association between triglyceride-glucose index and all-cause mortality in critically ill patients with acute myocardial infarction: analysis of the MIMIC-IV database [6]儿童重症监护室深部真菌感染死亡危险因素分析 [7]Impact of the triglyceride-glucose index on 28-day mortality in non-diabetic critically Ill patients with sepsis: a retrospective cohort analysis [8]Gender- and age-based differences in outcomes of mechanically ventilated ICU patients: a Chinese multicentre retrospective study. [9]Association between stress hyperglycemia ratio and contrast-induced nephropathy in ACS patients undergoing PCI: a retrospective cohort study from the MIMIC-IV database [10]Investigating the impact of ramelteon on all-cause mortality in ischemic stroke ICU patients: a retrospective propensity-matched study from the MIMIC-IV database

资源点击量:18261 今日访问量:0 总访问量:1004 更新日期:2025-11-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 首都医科大学宣武医院 技术支持:重庆聚合科技有限公司 地址:北京市西城区长椿街45号宣武医院