机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University,Beijing 100000, China神经科系统神经内科首都医科大学宣武医院[2]Beijing Key Laboratory of Neuromodulation, Beijing100000, China[3]Center of Epilepsy, Beijing Institute of Brain Disorders, CapitalMedical University, Beijing 100000, China[4]Department of Neurology, WestChina Hospital, Sichuan University, Chengdu 610000, China[5]Neuroelectrophysiological Laboratory, Xuanwu Hospital, Capital MedicalUniversity, Beijing 100000, China首都医科大学宣武医院[6]Department of Neurosurgery, GeneralHospital of PLA, Beijing 100000, China[7]Department of FunctionalNeurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100000,China神经科系统神经外科首都医科大学宣武医院[8]Epilepsy Center, Tsinghua University Yuquan Hospital, Beijing 100000,China[9]Department of Neurology, Beijing Tiantan Hospital, Capital MedicalUniversity, Beijing 100000, China首都医科大学附属天坛医院[10]China National Clinical Research Centerfor Neurological Disease NCRC-ND, Beijing 100000, China[11]Department ofPediatrics, Peking University First Hospital, Beijing 100000, China[12]EpilepsyCenter, Second Affiliated Hospital, School of Medicine, Zhejiang University,Hangzhou 310000, China[13]Department of Neurology, Shenzhen Children’sHospital, Shenzhen 518000, China深圳市康宁医院深圳医学信息中心[14]Section of Epilepsy, NeurologicalInstitute, Taipei Veterans General Hospital, Taipei, China[15]MEG Center,Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45245, USA[16]Division of Neurology, Cincinnati Children’s Hospital Medical Center,Cincinnati, OH 45245, USA
Studies in animal models of epilepsy and pre-surgical patients have unanimously found a strong correlation between high-frequency oscillations (HFOs, > 80 Hz) and the epileptogenic zone, suggesting that HFOs can be a potential biomarker of epileptogenicity and epileptogenesis. This consensus includes the definition and standard detection techniques of HFOs, the localizing value of pathological HFOs for epileptic foci, and different ways to distinguish physiological from epileptic HFOs. The latest clinical applications of HFOs in epilepsy and the related findings are also discussed. HFOs will advance our understanding of the pathophysiology of epilepsy.
基金：
This consensus was supported by the National Key R&D Program (No.2018YFC1314500) and the National Natural Science Foundation of China (No.81701297, 81801124).
第一作者机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University,Beijing 100000, China[2]Beijing Key Laboratory of Neuromodulation, Beijing100000, China[3]Center of Epilepsy, Beijing Institute of Brain Disorders, CapitalMedical University, Beijing 100000, China
通讯作者：
通讯机构：[1]Department of Neurology, Xuanwu Hospital, Capital Medical University,Beijing 100000, China[2]Beijing Key Laboratory of Neuromodulation, Beijing100000, China[3]Center of Epilepsy, Beijing Institute of Brain Disorders, CapitalMedical University, Beijing 100000, China
推荐引用方式(GB/T 7714)：
Wang Yuping,Zhou Dong,Yang Xiaofeng,et al.Expert consensus on clinical applications of high-frequency oscillations in epilepsy[J].ACTA EPILEPTOLOGICA.2020,2(1):doi:10.1186/s42494-020-00018-w.
APA：
Wang, Yuping,Zhou, Dong,Yang, Xiaofeng,Xu, Xin,Ren, Liankun...&Xiang, Jing.(2020).Expert consensus on clinical applications of high-frequency oscillations in epilepsy.ACTA EPILEPTOLOGICA,2,(1)
MLA：
Wang, Yuping,et al."Expert consensus on clinical applications of high-frequency oscillations in epilepsy".ACTA EPILEPTOLOGICA 2..1(2020)
