机构：[1]Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China[2]Department of Molecular Diagnostics and Biopharmaceutics, College of Pharmacy, Soochow University, Suzhou, Jiangsu, China[3]IPS Therapeutique Inc., Sherbrooke, QC, Canada JIE 4K8
Osteoporosis has until now been considered to be a disease associated with abnormal calcium metabolism. However, an increasing number of clinical observations strongly suggest the association of iron overload with bone diseases, particularly in osteoporosis in menopausal women. The recent identification of hepcidin sheds new light into the crucial role of iron homeostasis in bone metabolism. Decreasing iron overload in cell studies as well as in animal experiments has been shown to improve bone cell metabolism and growth in vitro and in vivo. In view of the significant iron overload found in the aging population, especially in females, the therapeutic potential of lowering iron overload for the treatment of osteoporosis is suggested.
第一作者机构：[1]Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
通讯作者：
通讯机构：[1]Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China[2]Department of Molecular Diagnostics and Biopharmaceutics, College of Pharmacy, Soochow University, Suzhou, Jiangsu, China
推荐引用方式(GB/T 7714)：
G. F. Li,Y. Z. Pan,P. Sirois,et al.Iron homeostasis in osteoporosis and its clinical implications[J].OSTEOPOROSIS INTERNATIONAL.2012,23(10):2403-8.doi:10.1007/s00198-012-1982-1.
APA：
G. F. Li,Y. Z. Pan,P. Sirois,K. Li&Y. J. Xu.(2012).Iron homeostasis in osteoporosis and its clinical implications.OSTEOPOROSIS INTERNATIONAL,23,(10)
MLA：
G. F. Li,et al."Iron homeostasis in osteoporosis and its clinical implications".OSTEOPOROSIS INTERNATIONAL 23..10(2012):2403-8
