机构：[a]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China神经外科首都医科大学宣武医院[b]Drug Clinical Trial Institution, Tianjin Huanhu Hospital, Tianjin, China[c]Department of Ultrasound, Xuanwu Hospital, Capital Medical University, Beijing, China首都医科大学宣武医院[d]Department of Traditional Chinese Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China首都医科大学宣武医院[e]China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China中美神经科学研究所首都医科大学宣武医院[f]Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA[g]Department of Neurological Surgery, University of California San Francisco, San Francisco, CA , USA[h]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China
Objective: There are limited studies exploring prognosis after intracerebral hemorrhage (ICH) in Chinese populations. Thus, we evaluated the risk factors and predictors of mortality and recurrent stroke in a large clinical cohort at a single institution. Methods: We analysed consecutive cases of spontaneous ICH at admission to our hospital from September 2010 to December 2016. Independent predictors of mortality at one month and five year follow-up, as well as stroke recurrence were analysed. Results: A total of 1187 cases were included (33.5% women). The one month case fatality rate was 12.5%, and the five year mortality rate was 22.2%. In the multivariate analysis, diabetes was an independent predictor of one month case fatality, and older age (z65 years) was an independent predictor of five year mortality. Brain stem hemorrhage and intraventricular hemorrhage were independent predictors of both short- and long-term mortality. The overall recurrence rate was 32.5% among one month survivors. Conclusion: Predictors of recurrent stroke were older females, hypertension, diabetes, and brain stem hemorrhage. These findings may help to determine specific treatment strategies and improve quality of health care for such patients.
基金：
Beijing Postdoctoral Research Foundation [2017ZZ120]; Beijing Municipal Natural Science Foundation [2164073]; Howard Hughes Medical Institute (HHMI)
第一作者机构：[a]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China
共同第一作者：
通讯作者：
通讯机构：[a]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China[h]Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China
推荐引用方式(GB/T 7714)：
Feng Yan,Zhang Yi,Yang Hua,et al.Predictors of mortality and recurrent stroke within five years of intracerebral hemorrhage[J].NEUROLOGICAL RESEARCH.2018,40(6):466-472.doi:10.1080/01616412.2018.1451266.
APA：
Feng Yan,Zhang Yi,Yang Hua,Ying Shen,Ming Li...&Wei Yue.(2018).Predictors of mortality and recurrent stroke within five years of intracerebral hemorrhage.NEUROLOGICAL RESEARCH,40,(6)
MLA：
Feng Yan,et al."Predictors of mortality and recurrent stroke within five years of intracerebral hemorrhage".NEUROLOGICAL RESEARCH 40..6(2018):466-472
