机构:[1]Zhongshan Hospital, Fudan University, Shanghai 200032, China.[2]Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, TX 76107, USA.[3]Department of Urology, the First Affiliated Hospital, Zhejiang University, Zhejiang Province, China.[4]Institute of Hypoxia Medicine, Xuanwu Hospital, Capital Medical University. Beijing, China.首都医科大学宣武医院[5]Buck Institute for Research on Aging, Novato, CA 94945, USA.[6]Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.
基金:
China Scholarship Council (No. 201406320118).
the American Heart Association Predoctoral Fellowship (15PRE25700416)
Sigma Xi Grants-in-Aid of Research (G201503151162287)
National Natural Science Foundation of China (81301996)
Programs Foundation of Ministry of Education of China (20130101120017)
第一作者机构:[1]Zhongshan Hospital, Fudan University, Shanghai 200032, China.[2]Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, TX 76107, USA.[*1]Zhongshan Hospital, Fudan University, Shanghai, China
通讯作者:
通讯机构:[*1]Zhongshan Hospital, Fudan University, Shanghai, China[*2]the First Affiliated Hospital, Zhejiang University, China.[*3]University of North Texas Health Science Center, Fort Worth, TX 76107, USA.
推荐引用方式(GB/T 7714):
Xianglai Xu,Brian Wang,Changhong Ren,et al.Age-related Impairment of Vascular Structure and Functions[J].AGING AND DISEASE.2017,8(5):590-610.doi:10.14336/AD.2017.0430.
APA:
Xianglai Xu,Brian Wang,Changhong Ren,Jiangnan Hu,David A. Greenberg...&Kunlin Jin.(2017).Age-related Impairment of Vascular Structure and Functions.AGING AND DISEASE,8,(5)
MLA:
Xianglai Xu,et al."Age-related Impairment of Vascular Structure and Functions".AGING AND DISEASE 8..5(2017):590-610