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Age-related Impairment of Vascular Structure and Functions

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机构: [1]Zhongshan Hospital, Fudan University, Shanghai 200032, China. [2]Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, TX 76107, USA. [3]Department of Urology, the First Affiliated Hospital, Zhejiang University, Zhejiang Province, China. [4]Institute of Hypoxia Medicine, Xuanwu Hospital, Capital Medical University. Beijing, China. [5]Buck Institute for Research on Aging, Novato, CA 94945, USA. [6]Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
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关键词: vascular aging vascular remodeling endothelial dysfunction arterial stiffness

摘要:
Among age-related diseases, cardiovascular and cerebrovascular diseases are major causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age is an independent and essential risk factor. The present work will review morphological alterations of aging vessels in-depth, which includes the discussion of age-related microvessel loss and changes to vasculature involving the capillary basement membrane, intima, media, and adventitia as well as the accompanying vascular dysfunctions arising from these alterations.

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出版当年[2016]版
大类 | 3 区 医学
小类 | 3 区 老年医学
最新[2023]版:
大类 | 2 区 医学
小类 | 3 区 老年医学
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出版当年[2015]版:
Q1 GERIATRICS & GERONTOLOGY
最新[2023]版:
Q1 GERIATRICS & GERONTOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

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第一作者机构: [1]Zhongshan Hospital, Fudan University, Shanghai 200032, China. [2]Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, TX 76107, USA. [*1]Zhongshan Hospital, Fudan University, Shanghai, China
通讯作者:
通讯机构: [*1]Zhongshan Hospital, Fudan University, Shanghai, China [*2]the First Affiliated Hospital, Zhejiang University, China. [*3]University of North Texas Health Science Center, Fort Worth, TX 76107, USA.
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