详情页 - 首都医科大学宣武医院知识库

当前位置：首页 > 详情页

Whole-brain voxel-based morphometry of white matter in mild cognitive impairment

文献详情

资源类型：

WOS体系：

收录情况： ◇ SCIE

作者：

机构： [a]Department of Radiology, Xuanwu Hospital of Capital Medical University, 100053, Beijing, China [b]College of Information Science and Technology, Beijing Normal University, 100875, Beijing, China [c]National Key Laboratory for Cognitive Neuroscience and Learning, Beijing Normal University, 100875, Beijing, China

出处：

DOI：

ISSN：

关键词： Voxel-based morphometry Magnetic resonance imaging Mild cognitive impairment

摘要：

Purpose: The purpose of this study was to analyze whole-brain white matter changes in mild cognitive impairment (MCI). Materials and methods: We studied 14 patients with MCI and 14 age-and sex-matched healthy control subjects using voxel-based morphometry (VBM) on T1-weighted 3D datasets. The data were collected on a 3T MR system and analyzed by SPM2 to generate white matter volume maps. Results: Voxel-based morphometry revealed diffusively reduced white matter in MCI prominently including the bilateral temporal gyrus, the right anterior cingulate, the bilateral superior and medial frontal gyrus and right parietal angular gyrus. White matter reduction was more prominent in anterior regions than that in posterior regions. Conclusion: Whole-brain white matter reduction in MCI patients detected with VBM has special distribution which is in line with the white matter pathology of MCI. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2009]版：

大类 | 4 区医学

小类 | 3 区核医学

最新[2023]版：

大类 | 3 区医学

小类 | 3 区核医学

JCR分区：

出版当年[2008]版：

Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

最新[2023]版：

Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子： 3.2 最新[2023版] 3.4 最新五年平均 2.339 出版当年[2008版] 2.456 出版当年五年平均 1.915 出版前一年[2007版] 2.645 出版后一年[2009版]

第一作者：

第一作者机构： [a]Department of Radiology, Xuanwu Hospital of Capital Medical University, 100053, Beijing, China

通讯作者：

通讯机构： [a]Department of Radiology, Xuanwu Hospital of Capital Medical University, 100053, Beijing, China

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]轻度认知功能损害的BOLD-fMRI研究进展 [2]Identifying Mild Cognitive Impairment with Random Forest by Integrating Multiple MRI Morphological Metrics. [3]影响扩散张量图像质量和相关参数测量准确性的因素 [4]ACE I/D polymorphism affects cognitive function and gray-matter volume in amnestic mild cognitive impairment [5]Structural and Functional Changes in Subcortical Vascular Mild Cognitive Impairment: A Combined Voxel-Based Morphometry and Resting-State fMRI Study [6]Change of olfactory function associated structures in Parkinson's disease: A voxel - Based morphometry study [7]Structural and Functional Changes in Subcortical Vascular Mild Cognitive Impairment: A Combined Voxel-Based Morphometry and Resting-State fMRI Study [8]Study of gray matter loss in alzheimer's disease based on automatic voxel-based morphometry [9]应用基于体素的形态测量学方法分析视神经脊髓炎患者的脑体积变化 [10]Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy