机构：[a]Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China放射科首都医科大学宣武医院[b]Institute of High Energy Physics, Chinese Academy of Sciences, China[c]Department of Neurology, Xuanwu Hospital, Capital University of Medical Sciences, China神经内科首都医科大学宣武医院
Purpose: The purpose of this study was to analyze whole-brain white matter changes in medial temporal lobe epilepsy (MTLE). Materials and methods: We studied 23 patients with MTLE and 13 age- and sex-matched healthy control subjects using voxel-based morphometry (VBM) on T1-weighted 3D datasets. The seizure focus was right sided in I I patients and left sided in 12. The data were collected on a 1.5 T MR system and analyzed by SPM 99 to generate white matter density maps. Results: Voxel-based morphometry revealed diffusively reduced white matter in MTLE prominently including bilateral frontal lobes, bilateral temporal lobes and corpus callosum. White matter reduction was also found in the bilateral cerebellar hemispheres in the left MTLE group. Conclusion: VBM is a simple and automated approach that is able to identify diffuse whole-brain white matter reduction in MTLE. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
第一作者机构：[a]Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China
通讯作者：
通讯机构：[a]Department of Radiology, Xuanwu Hospital, Capital University of Medical Sciences, Beijing 100053, China
推荐引用方式(GB/T 7714)：
Aihong Yu,Kuncheng Li,Lin Li,et al.Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy[J].EUROPEAN JOURNAL OF RADIOLOGY.2008,65(1):86-90.doi:10.1016/j.ejrad.2007.04.011.
APA：
Aihong Yu,Kuncheng Li,Lin Li,Baoci Shan,Yuping Wang&Sufang Xue.(2008).Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy.EUROPEAN JOURNAL OF RADIOLOGY,65,(1)
MLA：
Aihong Yu,et al."Whole-brain voxel-based morphometry of white matter in medial temporal lobe epilepsy".EUROPEAN JOURNAL OF RADIOLOGY 65..1(2008):86-90
