机构:[a]Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, MOE Key Laboratory of Major Diseases in Children, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China临床科室科研平台职能科室耳鼻咽喉头颈外科临床流行病与循证医学中心儿科研究所首都医科大学附属北京儿童医院[b]National Tuberculosis Reference Laboratory, Chinese Center for Disease Control and Prevention, Beijing, China
Treatment efficacy of Mycobacterium abscessus infections depends on bacterial genotype. Here, the relationship between genotype, as determined by sequence analysis, and antibiotic resistance phenotype was analyzed. The results demonstrate that M. abscessus genotype characteristics, including erm(41) sequevar and mutations of rrl and rrs, are predictive of clarithromycin and amikacin resistance.
基金:
Beijing Health System Top Level Health Technical Personnel Training Plan [20153079]; national basic research program of ChinaNational Basic Research Program of China [2014CB744403]; national science and technology major project [2014ZX100030002]
第一作者机构:[a]Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, MOE Key Laboratory of Major Diseases in Children, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China
通讯作者:
通讯机构:[a]Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, MOE Key Laboratory of Major Diseases in Children, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, China[b]National Tuberculosis Reference Laboratory, Chinese Center for Disease Control and Prevention, Beijing, China
推荐引用方式(GB/T 7714):
Zheng Huiwen,Liu Dongxin,Lu Jie,et al.Genetic Correlation of Antibiotic Susceptibility and Resistance Genotyping for the Mycobacterium abscessus Group[J].ANTIMICROBIAL AGENTS AND CHEMOTHERAPY.2019,63(1):-.doi:10.1128/AAC.01523-18.
APA:
Zheng, Huiwen,Liu, Dongxin,Lu, Jie,Song, Yuanyuan,Wang, Shengfen...&Ni, Xin.(2019).Genetic Correlation of Antibiotic Susceptibility and Resistance Genotyping for the Mycobacterium abscessus Group.ANTIMICROBIAL AGENTS AND CHEMOTHERAPY,63,(1)
MLA:
Zheng, Huiwen,et al."Genetic Correlation of Antibiotic Susceptibility and Resistance Genotyping for the Mycobacterium abscessus Group".ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 63..1(2019):-