机构：[1]Imaging Center, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56, Nanlishi Road, Xicheng District, Beijing 100045, China医技科室职能科室临床流行病与循证医学中心医学影像中心首都医科大学附属北京儿童医院[2]Department of Ophthalmology, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56, Nanlishi Road, Xicheng District, Beijing 100045, China临床科室职能科室临床流行病与循证医学中心眼科首都医科大学附属北京儿童医院[3]Department of Otolaryngology, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56, Nanlishi Road, Xicheng District, Beijing 100045, China临床科室职能科室耳鼻咽喉头颈外科临床流行病与循证医学中心首都医科大学附属北京儿童医院[4]Department of Hematology, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56, Nanlishi Road, Xicheng District, Beijing 100045, China医技科室职能科室临床流行病与循证医学中心血液中心首都医科大学附属北京儿童医院
To evaluate the clinical application of a full model-based iterative reconstruction (MBIR) algorithm in the ultra-low-dose paranasal sinus CT imaging of children. In the first phase, 16 low-dose CT dacryocystography (DCG) (80 kV/64 mAs) scans were reconstructed with MBIR and filtered back-projection (FBP) to demonstrate noise reduction capability of MBIR. MBIR images were also compared with the images of 21 standard-dose paranasal sinus patients reconstructed with adaptive statistical iterative reconstruction (ASIR) algorithm. In the second phase, 14 pediatric tumors patients (images with ASIR in the initial scan) who came for follow-up paranasal sinus CT scan were prospectively enrolled with reduced radiation and MBIR algorithm. In both study phases, image noise and the contrast noise ratio (CNR) of sphenoid was measured; and subjective image quality was evaluated. CTDIvol and DLP were recorded, and effective dose calculated. The CTDIvol value for the DCG group was 63.9% lower than the standard-dose sinus group (1.09 +/- 0.01 mGy vs. 3.02 +/- 0.35 mGy). Compared with the ASIR reconstruction in the standard-dose sinus patient group, images with MBIR in the ultra-low-dose DCG group had 39.9% lower noise (9.5 +/- 0.8HU vs. 15.8 +/- 3.3HU) and 63.6% higher CNR (14.4 +/- 4.7 vs. 8.8 +/- 2.2), with similar subjective image quality score. For the tumor patients, 65.5% dose reduction was achieved. Subjective quality scores were similar between the initial and follow-up scans. Objective noise was significantly lower for the follow-up group. MBIR provided equal or better image quality with significantly reduced radiation dose in paranasal sinus CT imaging of pediatric patients compared with standard-dose CT with ASIR algorithm.
基金：
Beijing Children's Hospital Young Investigator Program [BCH-YIPB-2016-06]; Clinical Technology Innovation Project of Beijing Municipal Commission [xmlx201407]
第一作者机构：[1]Imaging Center, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56, Nanlishi Road, Xicheng District, Beijing 100045, China
通讯作者：
通讯机构：[1]Imaging Center, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, No. 56, Nanlishi Road, Xicheng District, Beijing 100045, China
推荐引用方式(GB/T 7714)：
Sun Jihang,Zhang Qifeng,Duan Xiaomin,et al.Application of a full model-based iterative reconstruction (MBIR) in 80 kVp ultra-low-dose paranasal sinus CT imaging of pediatric patients[J].RADIOLOGIA MEDICA.2018,123(2):117-124.doi:10.1007/s11547-017-0812-0.
APA：
Sun, Jihang,Zhang, Qifeng,Duan, Xiaomin,Zhang, Chengyue,Wang, Pengpeng...&Peng, Yun.(2018).Application of a full model-based iterative reconstruction (MBIR) in 80 kVp ultra-low-dose paranasal sinus CT imaging of pediatric patients.RADIOLOGIA MEDICA,123,(2)
MLA：
Sun, Jihang,et al."Application of a full model-based iterative reconstruction (MBIR) in 80 kVp ultra-low-dose paranasal sinus CT imaging of pediatric patients".RADIOLOGIA MEDICA 123..2(2018):117-124
医学