This study investigated the mechanisms of resistance of 36 quinolone-resistant Salmonella Typhimurium strains isolated from outpatients with infectious diarrhea in Beijing Tian Tan Hospital between 2013 and 2015. The resistance spectrum of the 36 strains was measured using a broth dilution method. Class 1 integrons harboring the beta-lactamase gene and mutations in quinolone resistance determining regions were also investigated. All 36 quinolone-resistant Salmonella Typhimurium strains were found to be multidrug-resistant and the majority of these strains harbored Class 1 integrons. These findings study suggests that strategies for determining resistance spectrums should be implemented with greater urgency.
第一作者机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Emergency Dept, Beijing 100050, Peoples R China
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tiantan Hosp, Emergency Dept, Beijing 100050, Peoples R China
推荐引用方式(GB/T 7714):
Yuan Jing,Guo Wei.Mechanisms of resistance to quinolones in Salmonella Typhimurium from patients with infectious diarrhea[J].MICROBIOLOGY AND IMMUNOLOGY.2017,61(3-4):138-143.doi:10.1111/1348-0421.12476.
APA:
Yuan, Jing&Guo, Wei.(2017).Mechanisms of resistance to quinolones in Salmonella Typhimurium from patients with infectious diarrhea.MICROBIOLOGY AND IMMUNOLOGY,61,(3-4)
MLA:
Yuan, Jing,et al."Mechanisms of resistance to quinolones in Salmonella Typhimurium from patients with infectious diarrhea".MICROBIOLOGY AND IMMUNOLOGY 61..3-4(2017):138-143