Purpose: To investigated the brain response patterns of modulation of GB37 (Guangming) and KI8 (Jiaoxin). Materials and Methods: An experiment using nonrepeated event-related fMRI design, wash, carried out on 28 subjects with electroacupuncture stimulation (EAS) at GB37 or KI8 on the left-leg. The discrete cosine transform and functional connectivity methods were adopted to detect the differences related with these two acupoints before and after the EAS. Results: Spatial patterns were distinct for EAS at the two acupoints, and the overlapping brain regions were mainly located in the posterior cingulate cortex (PCC) and precuneus (pC). Two opposite patterns of modulation in the default mode network were detected from the temporal patterns with the overlapping PCC/pC as the region of interest. Furthermore, the specific responses of sustained effects at these acupoints were also identified. Conclusion: Spatial and temporal patterns of the sustained effect modulation of GB37 and KI8 were distinct. We suggest these findings may attribute to the functional specificity of a certain acupoint. Moreover. our current results reflect a significant methodological contribution to future acupuncture studies.
基金：
Project for the National Key Basic Research and Development Program (973)National Basic Research Program of China [2006CB705700]; Changjiang Scholars and Innovative Research Team in University (PCSIRT)Program for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT0645]; Chair Professors of Cheung Kong Scholars Program; CAS Hundred Talents ProgramChinese Academy of Sciences; CAS Scientific Research Equipment Develop Program [YZ0642, YZ200766]; 863 ProgramNational High Technology Research and Development Program of China [2008AA01Z411]; Joint Research Fund for Overseas Chinese Young Scholars [30528027]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [30672690, 30600151, 30873462, 30870685, 60532050, 60621001, 90209008]; Beijing Natural Science FundBeijing Natural Science Foundation [4071003]
第一作者机构：[2]Northeastern Univ, Sch Sino Dutch Biomed & Informat Engn, Shenyang, Liaoning, Peoples R China;
通讯作者：
通讯机构：[1]Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China;[3]Xidian Univ, Life Sci Res Ctr, Sch Elect Engn, Xian, Shaanxi, Peoples R China;[7]Chinese Acad Sci, Inst Automat, Zhong Guancun E Rd 95,POB 2728, Beijing 100190, Peoples R China
推荐引用方式(GB/T 7714)：
Liu Peng,Qin Wei,Zhang Yi,et al.Combining Spatial and Temporal Information to Explore Function-Guide Action of Acupuncture Using fMRI[J].JOURNAL OF MAGNETIC RESONANCE IMAGING.2009,30(1):41-46.doi:10.1002/jmri.21805.
APA：
Liu, Peng,Qin, Wei,Zhang, Yi,Tian, Jie,Bai, Lijun...&Liu, Yijun.(2009).Combining Spatial and Temporal Information to Explore Function-Guide Action of Acupuncture Using fMRI.JOURNAL OF MAGNETIC RESONANCE IMAGING,30,(1)
MLA：
Liu, Peng,et al."Combining Spatial and Temporal Information to Explore Function-Guide Action of Acupuncture Using fMRI".JOURNAL OF MAGNETIC RESONANCE IMAGING 30..1(2009):41-46
