机构:[1]Chinese Acad Med Sci, Inst Basic Med Sci, Key Lab Med Mol Biol, Dept Pathophysiol,Sch Basic Med, Beijing 100730, Peoples R China;[2]Capital Med Univ, Beijing Anzhen Hosp, Dept Nephrol, Beijing, Peoples R China;临床科室肾内科首都医科大学附属安贞医院[3]Peking Union Med Coll Hosp, Dept Nephrol, Beijing, Peoples R China;[4]Chinese Acad Med Sci, Inst Basic Med Sci, Key Lab Med Mol Biol, Dept Pathophysiol,Sch Basic Med, 5 Dong Dan San Tiao, Beijing 100730, Peoples R China
Research on the human urine proteome may lay the foundation for the discovery of relevant disease biomarkers. Posttranslational modifications (PTMs) have important effects on the functions of protein biomarkers. Identifying PTMs without enrichment adds no extra steps to conventional identification procedures for urine proteomics. The only difference is that this method requires software that can conduct unrestrictive identifications of PTMs. These PTMs include methylation, dehydration, oxidation, hydroxylation, phosphorylation, or dihydroxylation. These data are useful reference for PTM biomarker discovery in the future.
第一作者机构:[1]Chinese Acad Med Sci, Inst Basic Med Sci, Key Lab Med Mol Biol, Dept Pathophysiol,Sch Basic Med, Beijing 100730, Peoples R China;
通讯作者:
通讯机构:[1]Chinese Acad Med Sci, Inst Basic Med Sci, Key Lab Med Mol Biol, Dept Pathophysiol,Sch Basic Med, Beijing 100730, Peoples R China;[4]Chinese Acad Med Sci, Inst Basic Med Sci, Key Lab Med Mol Biol, Dept Pathophysiol,Sch Basic Med, 5 Dong Dan San Tiao, Beijing 100730, Peoples R China
推荐引用方式(GB/T 7714):
Liu Liu,Liu Xuejiao.Urinary Proteins with Post-translational Modifications[J].ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY.2015,845:59-65.doi:10.1007/978-94-017-9523-4_6.
APA:
Liu, Liu&Liu, Xuejiao.(2015).Urinary Proteins with Post-translational Modifications.ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY,845,
MLA:
Liu, Liu,et al."Urinary Proteins with Post-translational Modifications".ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 845.(2015):59-65