详情页 - 首都医科大学宣武医院知识库

当前位置：首页 > 详情页

Intractable diseases treated with intra-bone marrow-bone marrow transplantation

文献详情

资源类型：

作者：

机构： [a]Department of Stem Cell Disorders, Kansai Medical University, Hirakata City, Japan [b]Department of Cardiac Surgery, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing Anzhen Hospital Affiliated to Capital Medical University, Beijing, China

出处：

DOI：

ISSN：

关键词： Autoimmune diseases Intra-bone marrow-bone marrow transplantation Malignant tumors Mesenchymal stem cell Rheumatoid arthritis

摘要：

Bone marrow transplantation (BMT) is used to treat hematological disorders, autoimmune diseases (ADs) and lymphoid cancers. Intra bone marrow-BMT (IBM-BMT) has been proven to be a powerful strategy for allogeneic BMT due to the rapid hematopoietic recovery and the complete restoration of T cell functions. IBM-BMT not only replaces hematopoietic stem cells (HSCs) but also mesenchymal stromal cells (MSCs). MSCs are multi-potent stem cells that can be isolated from bone marrow (BM), umbilical cord blood (UCB), and adipose tissue. MSCs play an important role in the support of hematopoiesis, and modify and influence the innate and adaptive immune systems. MSCs also differentiate into mesodermal, endodermal and ectodermal lineage cells to repair tissues. This review aims to summarize the functions of BM-derived-MSCs, and the treatment of intractable diseases such as rheumatoid arthritis (RA) and malignant tumors with IBM-BMT. © 2014 Li, Guo and Ikehara.

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2013]版：

无

最新[2023]版：

大类 | 2 区生物学

小类 | 2 区发育生物学 3 区细胞生物学

第一作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]心脏移植后骨髓腔内供者骨髓移植诱导供者特异性免疫低反应性再探讨 [2]CRL2APPBP2-mediated TSPYL2 degradation counteracts human mesenchymal stem cell senescence [3]Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis [4]指甲糖化蛋白浓度与类风湿关节炎临床表现关系研究 [5]Catheter ablation of atrial fibrillation in patients with rheumatoid arthritis [6]Rheumatoid Arthritis and Cardio-Cerebrovascular Disease: A Mendelian Randomization Study [7]Rs548234 polymorphism at PRDM1-ATG5 region susceptible to rheumatoid arthritis in Caucasians is not associated with rheumatoid arthritis in Chinese Han population [8]瓜氨酸化修饰对纤维蛋白原多肽抗原性的影响 [9]活动期类风湿性关节炎患者血脂代谢特点分析 [10]Remission of rheumatoid arthritis and potential determinants: a national multi-center cross-sectional survey