Objective: Clinical and pathological study of cystic metastatic carcinomas in the brain. Methods: There were 3 males and one female. The age were 28~49 years old. Multicystic lesions in brain were showed by CT and/or MRI. One case was operated upon and 3 cases were biopsied by stereotactic aspiration. All samples were observed on the light microscope. Result: There were 3 cases were diagnosed as metastatic small cell carcinoma in the brain and one case was diagnosed as brain metastases from adenoid cystic carcinoma in the lung. Conclusion: Cystic lesions in the brain may be one of pattern of metastases of brain and CT stereotactic aspiration play a role in accurate diagnosis of this lesions.