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Clinical research methods for treatment, diagnosis, prognosis, etiology, screening, and prevention: A narrative review

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机构: [1]Department of Oncology, McMaster University, Hamilton, Ontario, Canada [2]Center for Clinical Practice Guideline Conduction and Evaluation, Children’s Hospital of Fudan University, Shanghai, P.R. China [3]Department of Health Research Methods, Evidence, and Impact,McMaster University, Hamilton, Ontario, Canada [4]Department of Pediatrics, University of Antioquia, Colombia [5]EditorialOffice, Chinese Journal of Evidence-Based Pediatrics, Children’s Hospital of Fudan University, Shanghai, P.R. China [6]Division of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China [7]Division of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, P.R. China [8]Division of Respirology, Tongren Hospital, Capital Medical University, Beijing, P.R. China [9]Division of Respirology, Xuanwu Hospital, Capital Medical University, Beijing, P.R. China [10]Division of Orthopedic Surgery, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, Canada
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关键词: clinical research methods diagnosis literature search prognosis treatment

摘要:
This narrative review is an introduction for health professionals on how to conduct and report clinical research on six categories: treatment, diagnosis/differential diagnosis, prognosis, etiology, screening, and prevention. The importance of beginning with an appropriate clinical question and the exploration of how appropriate it is through a literature search are explained. There are three methodological directives that can assist clinicians in conducting their studies from a methodological perspective: (1) how to conduct an original study or a systematic review, (2) how to report an original study or a systematic review, and (3) how to assess the quality or risk of bias for a previous relevant original study or systematic review. This methodological overview article would provide readers with the key points and resources regarding how to perform high-quality research on the six main clinical categories. © 2020 Chinese Cochrane Center, West China Hospital of Sichuan University and John Wiley & Sons Australia, Ltd

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大类 | 2 区 医学
小类 | 2 区 医学:内科
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Q1 MEDICINE, GENERAL & INTERNAL

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第一作者机构: [1]Department of Oncology, McMaster University, Hamilton, Ontario, Canada [2]Center for Clinical Practice Guideline Conduction and Evaluation, Children’s Hospital of Fudan University, Shanghai, P.R. China [3]Department of Health Research Methods, Evidence, and Impact,McMaster University, Hamilton, Ontario, Canada [*1]Department of Oncology,McMaster University, 711 Concession Street, Hamilton, L8V 1C3,ON, Canada.
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通讯机构: [*1]Department of Oncology,McMaster University, 711 Concession Street, Hamilton, L8V 1C3,ON, Canada.
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