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Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations (Open Access)

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机构： [1]Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands [2]Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands [3]Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Disorders, Beijing, China [4]School of Rehabilitation Science,McMaster University, Hamilton, Ontario, Canada [5]Centre for Healthy Brain Ageing and Dementia Centre for Research Collaboration, School of Psychiatry, UNSW, Sydney, Australia [6]Centre for Research in Ageing and Cognitive Health, College of Medicine and Health, University of Exeter, Exeter, UK [7]Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA [8]Medical School, University ofWestern Australia, Perth,Western Australia, Australia [9]Normandie Univ, UNICAEN, INSERM, U1237, PhIND “Physiopathology and Imaging ofNeurological Disorders,”Institut Blood and Brain@Caen-Normandie, Cyceron, Caen, France [10]Section on Nutrition and Nutritional Epidemiology, Department of Internal Medicine, Rush University, Chicago, Illinois, USA [11]Department of Neurology, Oregon Health and Science University, Portland,Oregon, USA [12]Department of Neurology, University of Michigan, Ann Arbor,Michigan, USA [13]Department of Psychiatry, Amsterdam University Medical Center, VUmc, Amsterdam, the Netherlands [14]Department of Psychiatry, University of Michigan and VA Ann Arbor Healthcare System, Ann Arbor,Michigan, USA [15]Academic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne,Melbourne, Victoria, Australia [16]Department of Rehabilitation, Aged and Extended Care, College of Medicine and Public HealthFlinders University, Adelaide, Australia [17]Lyon Neuroscience Research Center INSERM U1028, CNRS UMR5292, Lyon University, Lyon, France [18]NorthWesternMental Health, Melbourne Health,Melbourne, Australia [19]Department of Child, Family, and Population Health Nursing, University ofWashington, Seattle,Washington, USA [20]Wisconsin Alzheimer’s Institute, University of Wisconsin-Madison School of Medicine and Public Health,Madison, Wisconsin, USA [21]Department of Psychology, University of New SouthWales, Randwick, Sydney, Australia [22]Neuroscience Research Australia, Sydney, Australia [23]The University of East Anglia, Norwich, UK [24]Department of Clinical, Educational & Health Psychology, University College London, London, UK [25]Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands [26]Department of Primary and Community Care, Radboud University Medical Center, Nijmegen, the Netherlands [27]Faculty of Fine Arts and Music, University of Melbourne,Melbourne, Victoria, Australia [28]Centre for Research on Ageing, Health, andWellbeing, Research School of Population Health,The Australian National University, Canberra, Australia

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关键词： cognitive rehabilitation cognitive stimulation therapy cognitive training cognitive-behavioral therapy for insomnia communication treatments framework meditation mild cognitive impairment multisensory treatments music-based treatments neuromodulation neuropsychiatric non-pharmacological nutritional interventions occupational therapy physical exercise training reminiscence therapy subjective cognitive decline

摘要：

Introduction: Non-pharmacological treatments (NPTs) have the potential to improve meaningful outcomes for older people at risk of, or living with dementia, but research often lacks methodological rigor and continues to produce mixed results. Methods: In the current position paper, experts in NPT research have specified treatment targets, aims, and ingredients using an umbrella framework, the Rehabilitation Treatment Specification System. Results: Experts provided a snapshot and an authoritative summary of the evidence for different NPTs based on the best synthesis efforts, identified main gaps in knowledge and relevant barriers, and provided directions for future research. Experts in trial methodology provide best practice principles and recommendations for those working in this area, underscoring the importance of prespecified protocols. Discussion: We conclude that the evidence strongly supports various NPTs in relation to their primary targets, and discuss opportunities and challenges associated with a unifying theoretical framework to guide future efforts in this area. © 2020 the Alzheimer's Association

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出版当年[2020]版：

大类 | 1 区

医学

小类 | 1 区临床神经病学

最新[2023]版：

大类 | 1 区

医学

小类 | 1 区临床神经病学

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出版当年[2019]版：

Q1 CLINICAL NEUROLOGY

最新[2023]版：

Q1 CLINICAL NEUROLOGY

影响因子： 13.1 最新[2023版] 16.1 最新五年平均 17.127 出版当年[2019版] 15.093 出版当年五年平均 14.423 出版前一年[2018版] 21.566 出版后一年[2020版]

第一作者：

第一作者机构： [1]Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands [2]Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands [*1]AmsterdamUniversity Medical Centers, Alex Bahar-Fuchs,University of Melbourne,Alzheimer Center Amsterdam,POBox 7057, 1007 MB,PK-1 Z052, Amsterdam, theNetherlands

通讯作者：

通讯机构： [*1]AmsterdamUniversity Medical Centers, Alex Bahar-Fuchs,University of Melbourne,Alzheimer Center Amsterdam,POBox 7057, 1007 MB,PK-1 Z052, Amsterdam, theNetherlands

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Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations (Open Access)

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