详情页 - 首都医科大学宣武医院知识库

当前位置：首页 > 详情页

Photoacoustic technologies in nervous system disorders: an emerging strategy for neuromodulation

文献详情

资源类型：

Pubmed体系：

收录情况： ◇ 统计源期刊 ◇ 卓越：梯队期刊

作者：

机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China. [2]Laboratory of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHNA-INI), Beijing, China. [3]Department of Chemistry, Guangdong-Hong Kong-Macao Joint Laboratory of Optoelectronic and Magnetic Functional Materials, Energy Institute and Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration & Reconstruction, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong Special Administrative Region, China. [4]Hong Kong University of Science and Technology-Shenzhen Research Institute, Shenzhen, Guangdong Province, China.

出处：

DOI：

ISSN：

关键词： neuromodulation optogenetics photoacoustic imaging photoacoustodynamic therapy spinal cord injury

摘要：

Spinal cord injury (SCI) is a severe neurological disorder; however, current treatment methods often fail to restore nerve function effectively. Spinal cord stimulation via electrical signals is a promising therapeutic modality for spinal cord injury. Based on similar principles, this review aims to explore the potential of optical and acoustic neuromodulation techniques, emphasizing their benefits in the context of spinal cord injury. Photoacoustic imaging, renowned for its noninvasive nature, high-resolution capabilities, and cost-effectiveness, is well recognized for its role in early diagnosis, dynamic monitoring, and surgical guidance in stem cell therapies for spinal cord injury. Moreover, photoacoustodynamic therapy offers multiple pathways for tissue regeneration. Optogenetics and sonogenetics use genetic engineering to achieve precise neuronal activation, while photoacoustoelectric therapy leverages photovoltaic materials for electrical modulation of the nervous system, introducing an innovative paradigm for nerve system disorder management. Collectively, these advancements represent a transformative shift in the diagnosis and treatment of spinal cord injury, with the potential to significantly enhance nerve function remodeling and improve patient outcomes.Copyright © 2025 Neural Regeneration Research.

基金：

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2025]版：

大类 | 2 区医学

小类 | 2 区细胞生物学 2 区神经科学

最新[2025]版：

大类 | 2 区医学

小类 | 2 区细胞生物学 2 区神经科学

第一作者：

第一作者机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China. [2]Laboratory of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHNA-INI), Beijing, China.

共同第一作者：

通讯作者：

通讯机构： [1]Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China. [2]Laboratory of Spinal Cord Injury and Functional Reconstruction, China International Neuroscience Institute (CHNA-INI), Beijing, China.

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Spinal Cord Stimulation for Pain Treatment After Spinal Cord Injury. [2]The Protective Effect of Spinal Cord Stimulation Postconditioning Against Spinal Cord Ischemia/Reperfusion Injury in Rabbits [3]Wireless Epidural Electrical Stimulation in Combination With Serotonin Agonists Improves Intraspinal Metabolism in Spinal Cord Injury Rats [4]Multidimensional review of cognitive impairment after spinal cord injury [5]Exoskeleton-assisted rehabilitation and neuroplasticity in spinal cord injury [6]Employing Endogenous NSCs to Promote Recovery of Spinal Cord Injury. [7]Quantitative MRI of the Spinal Cord and Brain in Chronic Traumatic Spinal Cord Injury: In Vivo Assessment of Structural Changes [8]Hyperbaric oxygen treatment of spinal cord injury in rat model [9]Brain White Matter Impairment in Patients with Spinal Cord Injury [10]Valproic acid-labeled chitosan nanoparticles promote recovery of neuronal injury after spinal cord injury