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Fabrication and evaluation of tissue engineering vascular scaffolds based on biodegradable aliphatic-aromatic copolyesters

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收录情况: ◇ SCIE ◇ CPCI(ISTP)

机构: [a]Beijing Institute of Technology, Beijing 100081, China [b]Institute of Vascular Surgery, Xuan Wu Hospital, Beijing 100053, China [c]National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China
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关键词: copolyester tissue engineering vascular scaffolds biocompatibility

摘要:
As initial step for developing tissue-engineered vascular autografts, a novel series of biodegradable aliphatic-aromatic copolyesters were synthesized and tubular scaffolds were fabricated. Cytotoxicity, adhesion and growth of different kinds of cells on the polyester films and in vivo biocompatibility have been evaluated. The results indicate that these copolyesters possess good biocompatibility. Canine bone marrow cells were seeded on the scaffolds and cultured in a bioreactor for 3 days. A confluent, adherent monolayer bone marrow cells was observed in the scaffold lumen. All the testing results suggest that these copolyesters might ultimately find applications for vascular tissue engineering. (c) 2005 Elsevier B.V. All rights reserved.

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最新[2025]版:
大类 | 4 区 物理与天体物理
小类 | 4 区 材料科学:综合 4 区 物理:应用
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Q2 PHYSICS, APPLIED Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY

影响因子: 最新[2024版] 最新五年平均 出版当年[2003版] 出版当年五年平均 出版前一年[2002版] 出版后一年[2004版]

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第一作者机构: [a]Beijing Institute of Technology, Beijing 100081, China
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通讯机构: [a]Beijing Institute of Technology, Beijing 100081, China
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