机构:[a]Beijing Institute of Technology, Beijing 100081, China[b]Institute of Vascular Surgery, Xuan Wu Hospital, Beijing 100053, China血管外科首都医科大学宣武医院[c]National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China
As initial step for developing tissue-engineered vascular autografts, a novel series of biodegradable aliphatic-aromatic copolyesters were synthesized and tubular scaffolds were fabricated. Cytotoxicity, adhesion and growth of different kinds of cells on the polyester films and in vivo biocompatibility have been evaluated. The results indicate that these copolyesters possess good biocompatibility. Canine bone marrow cells were seeded on the scaffolds and cultured in a bioreactor for 3 days. A confluent, adherent monolayer bone marrow cells was observed in the scaffold lumen. All the testing results suggest that these copolyesters might ultimately find applications for vascular tissue engineering. (c) 2005 Elsevier B.V. All rights reserved.
基金:
the National Hi-Tech ‘‘863’’ Plan (2001AA216077) and Beijing Science and Technology Committee (H020920040330).
第一作者机构:[a]Beijing Institute of Technology, Beijing 100081, China
通讯作者:
通讯机构:[a]Beijing Institute of Technology, Beijing 100081, China
推荐引用方式(GB/T 7714):
Liancai Wang,Yingfeng Wu,Liang Chen,et al.Fabrication and evaluation of tissue engineering vascular scaffolds based on biodegradable aliphatic-aromatic copolyesters[J].CURRENT APPLIED PHYSICS.2005,5(5):557-560.doi:10.1016/j.cap.2005.01.032.
APA:
Liancai Wang,Yingfeng Wu,Liang Chen,Yongquan Gu,Tingfei Xi...&Zeng-guo Feng.(2005).Fabrication and evaluation of tissue engineering vascular scaffolds based on biodegradable aliphatic-aromatic copolyesters.CURRENT APPLIED PHYSICS,5,(5)
MLA:
Liancai Wang,et al."Fabrication and evaluation of tissue engineering vascular scaffolds based on biodegradable aliphatic-aromatic copolyesters".CURRENT APPLIED PHYSICS 5..5(2005):557-560