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Motor Cortex Stimulation Therapy for Relief of Central Post-Stroke Pain: A Retrospective Study with Neuropathic Pain Symptom Inventory.

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收录情况： ◇ SCIE

作者：

机构： [a]Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing Institute of Functional Neurosurgery, Beijing, China [b]Department of Neurosurgery, Shenzhen University General Hospital, Shenzhen University, Shenzhen, China

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关键词： Motor cortex stimulation Central post-stroke pain Neuropathic pain symptom inventory Mechanism Predictor

摘要：

Motor cortex stimulation (MCS) has been used in the treatment of chronic neuropathic pain for more than 25 years. However, the mechanisms and outcome predictors still represent major challenges. To investigate outcome predictors and potential mechanisms of MCS on central post-stroke pain (CPSP). 16 CPSP patients were analyzed at our center. The pain intensity was assessed using a visual analog scale (VAS) before surgery and at the last follow-up. The Neuropathic Pain Symptom Inventory (NPSI) was used to assess pain intensity, analyze outcome predictors, and indicate potential mechanisms of MCS. The mean VAS score before surgery (8.0 ± 0.7) was significantly higher than that of the last follow-up (5.3 ± 2.4, p < 0.001). Similarly, the mean total NPSI score before MCS (30.6 ± 12.2) was significantly reduced at the last follow-up (25.2 ± 15.1, p = 0.01). An analysis of the NPSI subscores revealed a significant association between burning pain relief and effective results (p = 0.041, Fisher's exact test). Burning pain relief might predict long-term results for the therapeutic use of MCS in CPSP. The substantia gelatinosa may play an important role in the modulation of pain relief mediated by MCS. © 2018 S. Karger AG, Basel.

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出版当年[2017]版：

大类 | 4 区医学

小类 | 3 区外科 4 区神经成像 4 区神经科学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区神经成像 4 区神经科学 4 区外科

JCR分区：

出版当年[2016]版：

Q3 SURGERY Q4 NEUROIMAGING Q4 NEUROSCIENCES

最新[2023]版：

Q2 SURGERY Q3 NEUROIMAGING Q4 NEUROSCIENCES

影响因子： 1.9 最新[2023版] 1.7 最新五年平均 1.692 出版当年[2016版] 1.812 出版当年五年平均 1.691 出版前一年[2015版] 1.648 出版后一年[2017版]

第一作者：

第一作者机构： [a]Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing Institute of Functional Neurosurgery, Beijing, China

通讯作者：

通讯机构： [a]Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing Institute of Functional Neurosurgery, Beijing, China [*1]No. 45 Changchun Street Xicheng District, Beijing,China

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