机构：[1]Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan[2]Division of Clinical Laboratory and Blood Transfusion, University Hospital of the Ryukyus, Okinawa, Japan[3]Department of Infectious Diseases, Respiratory, and Digestive Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan[4]Control and Prevention of Infectious Disease, University Hospital of the Ryukyus, Okinawa, Japan[5]Department of Infectious Diseases, Faculty of the Ryukyus, Okinawa, Japan[6]Okinawa Institute of Advanced Science, Okinawa, Japan[7]Department of Genome Medicine, Research Institute, National Center for Children Health and Development, Tokyo, Japan
The mcr-1 gene encodes a phosphoethanolamine transferase that confers resistance to colistin by transferring phosphoethanolamine to lipid A. A 33-kb IncX4 plasmid harboring mcr-1 was detected in a Klebsiella pneumoniae isolate and two Escherichia coli isolates, and a 66-kb IncI2 plasmid was detected in three E. coli isolates in hospitals in Okinawa, Japan. (c) 2018 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
基金：
Okinawa Communicable Disease Research Hub Formation Promotion Project; Japan Society for the Promotion of ScienceMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science [18K07120]; Research Program on Emerging and Re-emerging Infectious Diseases of the Japan Agency for Medical Research and DevelopmentJapan Agency for Medical Research and Development (AMED) [18fk0108061]
第一作者机构：[1]Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan
通讯作者：
通讯机构：[1]Department of Microbiology, Juntendo University School of Medicine, Tokyo, Japan[*1]Department of Microbiology, Faculty of Medicine, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113-8421, Japan
推荐引用方式(GB/T 7714)：
Tada Tatsuya,Uechi Kohei,Nakasone Isamu,et al.Emergence of IncX4 plasmids encoding mcr-1 in a clinical isolate of Klebsiella pneumoniae in Japan[J].INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES.2018,75:98-100.doi:10.1016/j.ijid.2018.08.011.
APA：
Tada, Tatsuya,Uechi, Kohei,Nakasone, Isamu,Nakamatsu, Masashi,Satou, Kazuhito...&Fujita, Jiro.(2018).Emergence of IncX4 plasmids encoding mcr-1 in a clinical isolate of Klebsiella pneumoniae in Japan.INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES,75,
MLA：
Tada, Tatsuya,et al."Emergence of IncX4 plasmids encoding mcr-1 in a clinical isolate of Klebsiella pneumoniae in Japan".INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES 75.(2018):98-100
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