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Histological and mechanical properties of autologous living tissue biotubes

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收录情况： ◇ SCIE

作者：

机构： [1]Departments of Urology,Xuanwu Hospital,Capital Medical University, Beijing 100053, P.R. China [2]Departments of Vascular Surgery,Xuanwu Hospital,Capital Medical University, Beijing 100053, P.R. China [3]Departments of Central Laboratory, Xuanwu Hospital,Capital Medical University, Beijing 100053, P.R. China

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关键词： tissue engineering autologous transplant small caliber biotube collagen

摘要：

The aim of this study was to explore and evaluate biotubes consisting of autologous tissues. The biotubes were prepared by intra-abdominally embedding silicon rods as moulds. The specimens were analyzed by mechanical tests, histological observation and superficial study. The intra-abdominal implantation of the silicone tubes readily stimulated the development of the biotubes. The biotubes consisted of collagen-rich extracellular matrices. Myofibroblasts appeared as elongated cells with circumferential or longitudinal orientations. Subsequent to one month of embedding, the thickness of the tube wall was 70-250 mu m. The burst strength was 1100 +/- 187 mmHg and the suturability was excellent. Biotubes that have the ability to be widely variable in their shapes are composed of autologous cells and glomerular extracellular matrices. Biotubes are ideal grafts for tissue engineering as they are able to avoid immunological rejection and are of sufficient mechanical strength.

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中科院(CAS)分区：

出版当年[2012]版：

大类 | 4 区医学

小类 | 4 区医学：研究与实验

最新[2023]版：

大类 | 4 区医学

小类 | 4 区医学：研究与实验

JCR分区：

出版当年[2011]版：

Q4 MEDICINE, RESEARCH & EXPERIMENTAL

最新[2023]版：

Q3 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子： 2.4 最新[2023版] 2.3 最新五年平均 0.206 出版当年[2011版] 0.206 出版当年五年平均 0 出版前一年[2010版] 0.344 出版后一年[2012版]

第一作者：

第一作者机构： [1]Departments of Urology,Xuanwu Hospital,Capital Medical University, Beijing 100053, P.R. China

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通讯作者：

通讯机构： [*1]Department of Vascular Surgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Beijing 100053, P.R. China

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