机构:[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China,重点科室诊疗科室神经病学中心首都医科大学附属天坛医院[2]China National Clinical Research Center for Neurological Diseases, Beijing, China,[3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[4]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China,[5]Beijing Center for Diseases Prevention and Control, Beijing, China
Background and Purpose: A large body of literature reported the association of particulate matter (PM) with stroke in high-income countries. Few studies have examined the association between PM and stroke in middle- and low-income countries and considered the types of stroke. In this study, we examined the short-term effects of particulate matter <2.5 mu m in diameter (PM2.5) and particulate matter < 10 mu m in diameter (PM10) on ischemic stroke mortality and hemorrhagic stroke mortality in Beijing, China. Methods: We used an ecological study design and quasi-Poisson generalized additive models to evaluate the association of PM2.5 and PM10 and cerebrovascular diseases mortality, as well as ischemic- and hemorrhagic stroke mortality. In the model, we controlled long-term and season trends, temperature, and relative humidity, the day of the week and air pollution. For cerebrovascular diseases mortality, we examined the effects stratified by sex and age with different lag days. Results: A total of 48,122 deaths for cerebrovascular disease (32,799 deaths for ischemic stroke and 13,051 deaths for hemorrhagic stroke) were included in the study. PM2.5 was associated with stroke mortality. The 10 mu g/m(3) increase of PM2.5 was associated with the increase of mortality, 0.27% (95% CI, 0.12-0.43%) for cerebrovascular diseases, 0.23% (95% CI, 0.04-0.42%) for ischemic stroke and 0.37% (95% CI, 0.07-0.67%) for hemorrhagic stroke -. The associations between PM(10)and mortality were also detected for cerebrovascular diseases and ischemic stroke, but not in hemorrhagic stroke. The stratified analysis suggested age and gender did not modify the effects of PM on mortality significantly. Conclusions: Our study suggested that short-term exposure to ambient PM was associated with the risk of stroke mortality.
基金:
Beijing Municipal Commission of Health and Family Planning [2016-1-2041]; Beijing Municipal Administration of Hospitals' Sail Plan [XMLX201712]; Ministry of Science and Technology of The People's Republic of ChinaMinistry of Science and Technology, China [2016YFC0901001, 2016YFC0901002, 2017YFC1307702]
第一作者机构:[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China,[2]China National Clinical Research Center for Neurological Diseases, Beijing, China,[3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[4]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China,
通讯作者:
通讯机构:[1]Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China,[2]China National Clinical Research Center for Neurological Diseases, Beijing, China,[3]Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China,[4]Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease, Beijing, China,
推荐引用方式(GB/T 7714):
Zhang Runhua,Liu Gaifen,Jiang Yong,et al.Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality[J].FRONTIERS IN NEUROLOGY.2018,9(OCT):-.doi:10.3389/fneur.2018.00827.
APA:
Zhang, Runhua,Liu, Gaifen,Jiang, Yong,Li, Gang,Pan, Yuesong...&Wang, Yongjun.(2018).Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality.FRONTIERS IN NEUROLOGY,9,(OCT)
MLA:
Zhang, Runhua,et al."Acute Effects of Particulate Air Pollution on Ischemic Stroke and Hemorrhagic Stroke Mortality".FRONTIERS IN NEUROLOGY 9..OCT(2018):-